The cees dekker Diaries

The cees dekker Diaries

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Midway through his job, Cees Dekker reinvented himself. Following yrs of hardcore physics, he shifted his concentrate to ‘nanobiology’ for the flip with the millennium. A term he coined himself, being a matter of truth.

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Our get the job done was immediately adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.

This yielded a breakthrough. In just just a few months, we were capable to measure transportation through someone single-walled carbon nanotube. Determined by low-temperature experiments by an excellent PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technology with an Lively study lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being authentic quantum wires with quite extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.

Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,

‘In the beginning we checked out Organic methods by using a Actual physical view and acted on The idea on the applications we knew. It took a couple of years in advance of we started Functioning far more on the massive Organic issues. I then started to get in touch with it nanobiology, a phrase that didn't exist at enough time.

Finding out DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.

The rotors harness Vitality from the nanoscale water and ion move that is definitely generated by a static chemical or electrochemical potential gradient from the nanopore, ceesdekker that happen to be set up via a salt gradient or utilized voltage, respectively. These synthetic nanoengines self-Arrange and operate autonomously in physiological ailments, suggesting approaches to developing Strength-transducing motors at nanoscale interfaces.

There was a person problem although — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule level, conducting polymers had been truly not these kinds of wonderful conductors, which was somewhat disappointing. We Consequently broadened our perspective to test to search out extra promising molecules.

‘The idea that There is certainly this type of matter as a beginning, an enormous bang, is previously a fascinating signpost to look at that there was a creator. But much more typically, and on The idea of pure rationality, I also arrive at a Christian interpretation of reality. An atheistic worldview is really a naturalistic worldview: basically, you can find only atoms and pure forces that we can easily evaluate.

2001, discovery of one-electron transistors at home temperature based on nanotubes; realization of first logic circuits with carbon nanotube devices; and discovery of the molecular structure of DNA restore enzymes with AFM

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2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations within the handedness of histone tetrasomes